Open access
Sep 2026
Far-field bioluminescent immune cell-mediated photodynamic therapy is limited by photon flux.
No detectable ROS generation or tumor cell cytotoxicity in vitro is observed using luciferase-engineered tumor-associated macrophages and verteporfin, and complementary Monte Carlo simulations show that achievable photon fluxes are several orders of magnitude below established thresholds for cytotoxic PDT.
Ji Tae Park, Sudip Timilsina, Rebecca C. Harman et al.
· Photochemistry and Photobiol... · 0 citations