Author

Jeremy W. Herzog

2 papers indexed here

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Open access Aug 2026

Modulating immune toxicity in ulcerative colitis using a small molecule RAB27A inhibitor

Abstract Background Recent evidence has shown that ulcerative colitis patients with increased neutrophil biomarkers are linked to complicated disease and refractory response. In the pathology of colitis, neutrophils are recruited to the colon and yield acute damage via reactive oxygen species (ROS), degranulation, and...

Meital Ben-David-Naim, Dan Bijaoui, Naomi Iluz et al. · Inflammatory Bowel Diseases · 0 citations

Open access Aug 2026

Defined human Clostridia consortia reverse colitis via dual effects of tryptophan metabolites on microbiota and immunity

SUMMARY Microbial dysbiosis and disrupted mucosal immune homeostasis are integrally involved in the pathogenesis of inflammatory bowel diseases (IBD). Live biotherapeutic products (LBPs) offer a potential therapeutic strategy to restore beneficial microbes and mitigate disease. We investigated the therapeutic efficacy...

A. Oka, G. Bongers, Y. Mishima et al. · Cell Host and Microbe · 0 citations