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Jeremy Yeoh

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Review Open access Oct 2026

Temporal assessment of spatial and single-cell transcriptomes identifies CD226-NECTIN2 T cell-cholangiocyte interaction in bile duct inflammation.

BACKGROUND AND AIMS Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are inflammatory bile duct disorders affecting mostly young adults that often lead to liver cirrhosis and cancer. Especially for PSC, pathogenic mechanisms remain unclear and treatment options are lacking. To better understan...

M. Jördens, K. S. Nordhus, J. Øgaard et al. · 0 citations

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