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Author

Jeroen S. Dickschat

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Sep 2026

Structural Basis of Cyclized C17 Precursor Recognition and Product Formation in Chlororaphen and Grimophan Biosynthesis

Terpene cyclases (TCs) typically transform acyclic oligoprenyl pyrophosphates through carbocationic cyclization cascades. However, recently discovered bacterial pathways generate compact, cyclized and stereochemically defined noncanonical intermediates through methyltransferases prior to TC catalysis, raising the que...

Ke-Xin Yang, M. Groll, Jeroen S. Dickschat · 0 citations
Open access Aug 2026

Evolutionary, Functional and Mechanistic Characterisation of Microbial Terpene Synthase-Like Genes From Springtails.

This study lays the foundation for future research on terpene biosynthesis in Collembola, an ancient lineage of arthropods by revealing several unusual mechanistic aspects such as the formation of a series of enantiomerically pure products besides one scalemic compound.

Min Wang, Clément Schneider, Zarley Rebholz et al. · 0 citations

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