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Author

Jessica B. Foster

2 papers indexed here

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Aug 2026

A CAR-T Tonic Signaling Code Predicts Anti-Tumor Efficacy in Diffuse Midline Glioma.

BACKGROUND Diffuse middle glioma (DMG or DIPG) is a fatal pediatric brain tumor. Although chimeric antigen receptor (CAR) T-cell therapy shows promise, clinical outcomes remain inconsistent due to premature exhaustion, underscoring a critical need to improve CAR-T persistence. A major barrier to CAR-T efficacy is antig...

Bing Deng, Xiaowen Zhong, Da-Zhuan Xin et al. · 0 citations
Sep 2026

Abstract B026: Utility of DNA Methylation-Based Diagnostic Classifiers for Cohort Selection in Pediatric Neuro-Oncology Research

/Purpose: DNA methylation-based central nervous system (CNS) tumor classifiers have become increasingly useful for pediatric CNS malignancies, complementing traditional histological and molecular tumor diagnostics. Here, we investigate additional roles for methylation-based classifiers to aid in cohort selection...

Patrick J. Beck, Jessica B. Foster · 0 citations

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