Author

Jessica Neely

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Open access Oct 2026

Advancing CD38 from a marker of disease activity to an active regulator of interferon responses in juvenile dermatomyositis

Juvenile dermatomyositis (JDM), the most common pediatric inflammatory myopathy, is driven by an overactive immune signaling pathway called type I interferon. Current treatment relies on broadly immunosuppressive agents that lack mechanistic specificity, often fail to achieve durable disease control, and can result in...

Brittany A. Moser, Chioma J. Madubata, Marissa Y. Chou et al. · bioRxiv · 0 citations

Open access Aug 2026

Integrating single-cell and bulk transcriptomic perturbation resources reveals complementary therapeutic spaces for drug repurposing

Integrating heterogeneous transcriptomic perturbation resources improves the robustness and interpretability of transcriptional drug repurposing and provides an openly available framework to support this integrated approach.

Enock Niyonkuru, U. Khan, Xin-Yu Tang et al. · Research Square · 0 citations