Screening for medicine and food homologous ingredients targeting ALDH2 to alleviate acute ethanol-induced liver injury
Background Alcoholic liver disease (ALD) is a major global health burden with limited therapeutic options. Aldehyde dehydrogenase 2 (ALDH2) plays a critical role in alcohol metabolism, and ALDH2 deficiency exacerbates alcohol-induced hepatic injury. Aim This study aimed to identify and validate natural ALDH2 activators...