The epithelial tree of the lung is shaped proximo-distally by airway smooth muscle cells (ASMCs), ductal myofibroblasts (DMFs), and, transiently, alveolar myofibroblasts (AMFs). Lineage tracing and snapshot imaging suggest the clearance of AMFs via apoptosis post-alveologenesis, although definitive evidence is lacking....
M. Gacha-Garay, Hui Liu, Scott E. Evans et al.· Cell Reports· 0 citations
LungChat is deployed as a hierarchical multi-agent architecture in which a supervisor decomposes natural-language questions into parallel, tool-grounded tasks spanning single-cell and spatial analyses, literature and clinical-trial synthesis, and drug repurposing.
Pankaj Rajdeo, S. Asanuma, Michal Kouril et al.· bioRxiv· 0 citations
A novel Biologically Interpretable multi-modal Graph using Spatial Transcriptomics, called BIGraph-ST, that integrates pathway activity scores and histological image features for robust spatial domain identification and provides biologically interpretable pathway-level representations of domains, which ultimately offer...
Seungeun Lee, Guolon Wang, Kyungtae Kang et al.· bioRxiv· 0 citations
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