Review
Open access
Oct 2026
Cartilage Extracellular Matrix Homeostasis in Knee Osteoarthritis: Pathomechanisms and Therapeutic Targeting
This review systematically examines the central role of CECM homeostasis in KOA pathogenesis and summarizes recent advances in this field, identifying multifaceted pathways driving CECM imbalance and highlighting promising multi‐modal therapeutic strategies.
Chao Du, Ji-Wei Zhong, Jia-Lin Yang et al.
· Journal of Cellular and Mole... · 0 citations