Author

Ji Hoon Jeong

2 papers indexed here

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Aug 2026

Discovery of synthetic TBK1 activator inducing type I interferon mediated antiviral and antitumor immunity.

Type I interferons (IFNs) are central regulators of innate immunity, coordinating antiviral defense and tumor immune surveillance. However, therapeutic strategies that selectively engage IFN signaling while maintaining controlled outputs remain limited. Here, we identify a synthetic small molecule that induces robust t...

Kwiwan Jeong, Subin Hong, Pin Liu et al. · Molecular Therapy · 0 citations

Open access Sep 2026

Enhanced Dissolution and Oral Bioavailability of Tegoprazan Using D-α-Tocopheryl Polyethylene Glycol 1000 Succinate-Based Melt Granulation System

Tegoprazan (TPZ) is a promising potassium-competitive acid blocker, but its pH-dependent low solubility often leads to erratic oral absorption. Although several hydrophilic polymer-based amorphous solid dispersions have been attempted to enhance dissolution, they often suffer from thermodynamic instability or rely on c...

M. Jeong, Tae Hyoung Kim, I. Yang et al. · Molecules · 0 citations