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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Ji-Jia Hu

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2 papers indexed here

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Review Aug 2026

Drug failure in diabetic kidney disease: translational barriers, target validation and trial de-risking strategies.

Diabetic kidney disease (DKD) remains a difficult therapeutic setting in nephrology, metabolism and clinical pharmacology. Standard care has moved from glucose- and blood-pressure-centred treatment toward disease-modifying therapy built around renin-angiotensin-aldosterone system (RAAS) blockade, sodium-glucose cotrans...

Hong-Tu Hu, Suyue Hou, Wen-Jie Chen et al. · 0 citations
Oct 2026

SIRT3 regulates GLS1 K311 acetylation to restrain glutamate-driven ferroptosis in renal fibrosis.

Renal tubulointerstitial fibrosis is a final common pathway of chronic kidney disease (CKD), but the metabolic mechanisms linking mitochondrial dysfunction to ferroptotic tubular injury remain incompletely defined. We found that a SIRT3-GLS1-glutamate-p53/SLC7A11 pathway links mitochondrial deacetylation to ferroptosis...

Miao Yan, Hong-Tu Hu, Cheng Chen et al. · 0 citations

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