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Author

Ji Li

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Open access Oct 2026

Extracellular lactate enhances IL-10 transcription via H4K5 lactylation and promotes an A2-like reactive-astrocyte phenotype after ischemic stroke.

BACKGROUND Ischemic stroke triggers a rapid rise in lactate levels in the brain tissue. The neuroprotective role of exogenous lactate administered during the reperfusion phase has recently garnered attention. A neuroprotective A2 phenotype of reactive astrocytes (RACs) is characterized by interleukin-10 (IL-10) upregul...

Jun-Yuan Wei, Yu-Meng Si, Ji Li et al. · 0 citations
Open access Aug 2026

MgFe-Layered Double Hydroxide-Reinforced Injectable GelMA Hydrogels Promote Calvarial Bone Regeneration with IL-10RA-JAK1-STAT3-Associated Osteoimmunomodulation

Findings support cation-engineered LDH hydrogels as promising injectable biomaterials, although pathway inhibition, protein-level validation, ion-release profiling, and long-term biosafety studies are needed to clarify the proposed mechanism.

Jia-Jie Zheng, Kang Wang, Hao Xu et al. · 0 citations
Conference Jul 2026

An LLM-Based Decision-Support System for Mitigating Document-Induced Human Error Risks in Flight Test Occupational Safety

Multi-version iteration and cross-aircraft configuration differences in flight test restriction documents pose significant challenges to crew situational awareness. This paper presents an intelligent parsing and multi-dimensional comparison system based on large language models. An anchor-driven hierarchical partitioni...

Zhi-Peng Cai, Chun-Yi Xu, Chang Li et al. · 0 citations

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