Author

Ji-Long Yang

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Open access Aug 2026

Immunotherapy-based salvage therapy in advanced soft tissue sarcoma after first-line chemotherapy: a retrospective single-center analysis with emphasis on undifferentiated pleomorphic sarcoma

Introduction Soft tissue sarcomas (STS) are rare mesenchymal malignancies with limited treatment options in advanced stages. Anthracycline-based chemotherapy remains the standard of care but yields modest outcomes with significant toxicity, underscoring the need for more effective strategies. Methods We retrospectively...

Zhi-Chao Liao, Jun Huang, Hao-Tian Liu et al. · Frontiers in Immunology · 0 citations

Review Open access Aug 2026

HLX07, a novel anti-EGFR antibody, for locally advanced and metastatic cutaneous squamous cell carcinoma: an open-label, multicenter, phase II trial

HLX07 monotherapy has demonstrated promising efficacy and a favorable safety profile in treating aCSCC, warranting further investigation in large-scale clinical studies.

Chang-Xing Li, Kang Zeng, Dong-Yuan Zhu et al. · Therapeutic Advances in Medi... · 0 citations

Clinical trial Open access Aug 2026

T cell receptor repertoire dynamics and newly identified functional regulators of autologous tumor-infiltrating lymphocyte therapy in advanced solid tumors

The efficacy of TIL therapy in diverse solid tumors among Asian patients is demonstrated, dynamic TCR clonal remodeling in responders is revealed, and ASS1 and CEP20 knockout as strategies to potentiate antitumor activity are identified.

Fen-Ge Li, Ji-Long Yang, Gregory A. Lizee et al. · Journal of Translational Med... · 0 citations