Sep 2026
Knockdown of CDC20 attenuates pulmonary fibrosis by repressing fibroblast activation via the TSC1-mediated mTOR pathway.
Overall, CDC20 exacerbated pulmonary fibrosis by inhibiting fibroblast autophagy via blocking the mTOR signaling pathway, which suggested that targeting CDC20 might hold putative therapeutic effect in IPF.
Ya-Tao Guo, Meng-Chan Zhu, Ru-Yi Li et al.
· Cellular Signalling · 0 citations