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Author

Ji-Peng Ding

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2 papers indexed here

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Oct 2026

An HOCl-responsive chemiluminescent probe for monitoring MPO-mediated HOCl generation for deep-tissue tracking and evaluation of inflammatory bowel disease.

By engineering the donor-acceptor scaffold of isoluminol, we developed 2TPA-IsoL, a novel chemiluminescent probe with red-shifted emission (600 nm), high HOCl selectivity, and prolonged kinetics. It enables deep-tissue imaging and therapeutic evaluation of inflammatory bowel disease, offering a generalizable strategy f...

Qiang-Chao Meng, Run-Sha Xiao, Ji-Peng Ding et al. · 0 citations
Open access Sep 2026

TRPML1 inhibitor ML-SI1 suppresses prostate cancer through dual regulation of androgen receptor and polyamine metabolism

Prostate cancer (PCa) is the second leading cause of cancer-related death in men worldwide, with metastasis and drug resistance representing major drivers of mortality. Transient receptor potential mucolipin 1 (TRPML1), a member of the transient receptor potential channel superfamily, is associated with several mal...

Jiong-Zheng Li, Ji-Peng Ding, Hong-Fei Wei et al. · 0 citations

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