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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Ji-Xing Liang

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Sep 2026

Melatonin ameliorates manganese-induced neurological deficits in mice by inhibiting TXNIP signaling-mediated neuroinflammation and microglial pyroptosis: Role of SIRT6.

Findings suggest that Mel mitigates Mn-associated hippocampal neuroinflammatory injury by partially restoring SIRT6-mediated epigenetic repression of Txnip and reducing TXNIP/NLRP3-driven microglial pyroptosis.

Jia Liu, Ji-Xing Liang, Ke-Yu Chen et al. · 0 citations

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