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Author

Jia-Bin Zhou

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Review Open access Jan 2026

FTH1 mRNA–Protein Discordance in Cardiac Ferroptosis: Multilayer Posttranscriptional and Degradative Control

Ferritin heavy Chain 1 (FTH1) is a key protective factor against ferroptosis in the heart, yet its protein abundance can diverge from transcript levels in cardiac ferroptosis contexts. Since resistance to ferroptosis depends on FTH1 protein abundance rather than transcript levels and its ferroxidase activity cannot be...

Feng Zhou, Jia-Bin Zhou, Yi-Qing Yan et al. · 0 citations
Open access Sep 2026

Ferroptosis Signatures in Diabetic Cardiomyopathy: Multi-Omics Discovery and Validation of ACOT1 and TXNIP

This study identifies Acot1 and Txnip as ferroptosis-related molecular signatures in DCM and provides multistep prioritization and validation spanning bulk transcriptomics, single-cell and spatial transcriptomics, and in vivo experimental verification, offering potential targets for ferroptosis-targeted therapeutic int...

Feng Zhou, Jia-Bin Zhou, Ling Zhang et al. · 0 citations

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