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Aug 2026

Targeting Peroxiredoxin 6: Tannic Acid Inhibits Singapore Grouper Iridovirus Infection via PRDX6-Dependent Pathway and Antioxidant Response.

Singapore grouper iridovirus (SGIV) is a major viral pathogen threatening grouper aquaculture. The lack of specific antiviral drugs underscores the urgent need to develop safe and effective control strategies. This study demonstrates that tannic acid (TA) exhibits significant anti-SGIV activity in vitro. In grouper spl...

Xiangmou Qin, Chen-Ao Li, Lin Huang et al. · 0 citations
Aug 2026

Dual Regulation of Lipid Metabolism and Mitochondrial Respiratory Chain: The roles of Ec-GRIM19 during RGNNV Infection in orange-spotted grouper (Epinephelus coioides).

Gene associated with retinoid-interferon-induced mortality 19 (GRIM19) can affect viral infection by regulating lipid metabolism, and modulate inflammatory factors via the mitochondrial respiratory chain. However, the function of fish GRIM19s remains unclear. In this study, the GRIM19 gene (Ec-GRIM19) was identified fr...

Zhi-Tong Yu, Xiaopiao Zhong, Wenze Li et al. · 0 citations

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