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Author

Jia-Fu Ji

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Review Aug 2026

Tumor-Derived Model Biobanks in China: Current Status and Future Challenges.

Tumor-derived model biobanks comprise patient-derived xenografts, organoids, cell models or cultures, and selected paired derivatives linked to clinical, pathological, molecular, and functional data. In China, patient-derived organoid and xenograft resources have expanded through clinical and academic studies, enterpri...

Lian-Hai Zhang, Ying Hu, Haixin Li et al. · 0 citations
Open access Jul 2026

Cisplatin-induced ecDNA enhances tumor malignancy and accelerates chemoresistance acquire in gastric cancer.

This study revealed that cisplatin could promote ecDNA generation, which enhanced malignant phenotypes, including cell proliferation, motility and drug resistance, and was associated with poorer patient prognosis, and targeting ecDNA with inhibitors could reverse these effects.

Huanbo Zhu, Lian Chen, Long-Tao Huangfu et al. · 0 citations

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