Nrf2 signaling: an important approach for the botanical drug and metabolites to ameliorate pulmonary hypertension via regulating pulmonary artery endothelial cells
Pulmonary hypertension (PH) is a life-threatening condition characterized by pulmonary vascular remodeling and elevated pulmonary artery pressure. Its pathophysiology is marked by a remarkable rise in pulmonary artery pressure and an escalating vascular resistance, ultimately leading to right-sided heart failure and an...