Jia Hua

Integrative single-cell and bulk transcriptomic profiling identify peripheral T-cell-associated candidate biomarkers in community-acquired pneumonia

Background Community-acquired pneumonia (CAP) is associated with marked immune dysregulation, but the peripheral T-cell transcriptional alterations linked to CAP remain incompletely defined. We aimed to characterize CAP-associated T-cell heterogeneity and identify candidate blood biomarkers by integrating single-cell a...