Discovery of Putative Phosphorylation Sites in Cre1 and Ace1 as Engineering Targets for Enhanced Cellulase Production in Trichoderma reesei
In the filamentous fungus Trichoderma reesei, cellulase production is subject to carbon catabolite repression (CCR) mediated by the key repressors Cre1 and Ace1. In this study, we identified two previously unreported phosphorylation sites—S204 in Cre1 and S145 in Ace1—through phosphoproteomic profiling. Site-directed m...