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Author

Jia-Hui Zhang

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Oct 2026

EGFR exon 20-altered NSCLC in China: molecular heterogeneity and real-world outcomes with sunvozertinib.

Real-world evidence is provided of the molecular and clinical heterogeneity of EGFR exon 20-altered NSCLC and a possible survival difference according to loop location and a potentially favorable association between sunvozertinib exposure and OS among non-surgical patients are highlighted.

Jia-Hui Zhang, Yue-Chen Cui, Qing Ren et al. · 0 citations
Open access Sep 2026

Pretreatment CT radiomics for prediction of pathological complete response after neoadjuvant chemoimmunotherapy in NSCLC: a multicenter study incorporating habitat analysis

Background Pathological complete response (pCR) after neoadjuvant chemoimmunotherapy (NACI) varies among patients with non-small cell lung cancer (NSCLC). This study aimed to quantify intratumoral heterogeneity using habitat analysis and to develop a pretreatment model for predicting pCR. Methods In this retrospective...

Sun-Yi Zheng, Shu-Yuan Huang, Jia-Hui Zhang et al. · 0 citations
Open access Aug 2026

Integrative single-cell and genomic analysis reveals NMB as a driver of metastatic adaptation in esophageal squamous cell carcinoma via metabolic rewiring and immune evasion

NMB serves as a key driver of metastatic adaptation in ESCC, conferring a survival advantage to tumor cells during metastatic colonization through genomic evolution and immune remodeling, with metabolic adaptation as a downstream consequence of genomic alterations.

Zhi-Kai Cao, Dong-Chen Tian, Long He et al. · 0 citations

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