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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Jiajun Chen

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2 papers indexed here

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Sep 2026

AMPK/Autophagy‐Dependent Pro‐Adipogenic Effect Coupled With Enhanced Lipid Mobilization and Thermogenesis Underlies the Dual Action of Canagliflozin Against Obesity

Canagliflozin (CANA) exhibits prominent anti‐obesity effects in clinical practice, yet its direct adipocyte‐intrinsic functions remain poorly understood. Here, we investigated the regulatory mechanism of CANA in adipogenesis and adipose tissue remodeling. We found that CANA promoted 3 T3‐L1 preadipocyte differentiation...

Jing-Sa Zhang, Yi-Lu Shou, Ya-Ling Tang et al. · 0 citations
Aug 2026

Kaempferol Counteracts Obesity and Impairs Adipogenesis by Suppressing PI3K/AKT/GSK3β-Mediated Mitotic Clonal Expansion and Attenuating Adipose Tissue Fibrosis.

Kaempferol, a widely present dietary flavonoid in numerous fruits and vegetables, possesses antiobesity potential with unclearly defined mechanisms. This study investigated how kaempferol regulates adipogenesis in 3T3-L1 preadipocytes and exerts antiobesity effects in high-fat diet (HFD)-induced obese mice. Kaempferol...

Xia Du, Ya-Ling Tang, Yi-Lu Shou et al. · 0 citations

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