Author

Jia-Jun Qiu

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Open access Aug 2026

Composite C-reactive protein-triglyceride-glucose adiposity indices and incident cardiovascular-liver-metabolic multimorbidity: a prospective cohort study

The C-reactive protein-triglyceride-glucose index (CTI) is a comprehensive marker that reflects inflammation and insulin resistance. Cardiovascular-liver-metabolic (CLM) diseases caused by multiple factors may be related to insulin resistance, obesity, metabolism, etc. Our aim is to explore the association between the...

Jing Chen, Zhong-Hua Sun, Jia-Jun Qiu et al. · Cardiovascular Diabetology · 0 citations

Open access Jul 2026

Association between the combined cholesterol, high-density lipoprotein, glucose index and frailty index and new-onset cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: evidence from CHARLS.

This study aimed to evaluate the association and predictive utility of the combined cholesterol, high-density lipoprotein, glucose index and frailty index (CHG-FI) for new-onset CVD, heart disease, and stroke among individuals with early-stage CKM syndrome.

Zhong-Hua Sun, Kexue Wang, Chiwei Guo et al. · Cardiovascular Diabetology · 0 citations

Jul 2026

METTL3‐Activated IDO1‐Kynurenine Pathway in Insulin‐Producing Cells Enhances Graft Survival and Attenuates Endogenous Islet Apoptosis in Diabetic Mice

It is shown that METTL3 overexpression is associated with IDO1 upregulation and elevated systemic Kyn levels, which suggest that the METTL3‐IDO1‐Kyn pathway may be a potential target for improving cell replacement therapy for diabetes.

Shan Xu, Li-Xuan Fang, Jia-Jun Qiu et al. · The FASEB Journal · 0 citations