Author

Jia-Kang He

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Aug 2026

Development of High-Affinity Monoclonal Antibodies for Aflatoxin M1 Detection in Milk.

Aflatoxin M1 (AFM1) in milk poses significant health risks due to its carcinogenicity and resistance to thermal processing. Here, we applied a computer-aided hapten design strategy integrating density functional theory, molecular docking, and molecular dynamics simulations to engineer four AFM1 haptens with tailored sp...

Zhi Zhao, Xiaoge Duan, Ting-Ting Yue et al. · Journal of Agricultural and... · 0 citations

Sep 2026

A novel chimeric antimicrobial peptide B5PL dual-targets bacterial cell membrane and neutrophils to combat multidrug-resistant bacterial infections.

Methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Klebsiella pneumoniae (MDR-KP) pose severe threats to global public health due to lack of effective therapeutic strategies. Conventional antibacterial agents exhibit limited potency for modulating host immune defense responses. This study design...

Ren-Ling Wang, Yun Yang, Yu-Ping Chen et al. · Bioorganic chemistry (Print) · 0 citations