Review
Aug 2026
Beyond Monotherapy: The Evolving Role of CTLA-4 in Combination Immunotherapy for Gastrointestinal Cancers.
CTLA-4 blockade with Ipilimumab or Tremelimumab shows promise, especially combined with PD-1/PD-L1 inhibitors, yielding enhanced antitumor immunity in microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR) tumors with high immune infiltration.
Fuyuan Ma, Jingyuan Ma, Yaofan Lu et al.
· American Journal of the Medi... · 0 citations