Author

Jia Li

3 papers indexed here

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Open access Jan 2026

Patient‐Derived iPSC‐Cardiomyocytes Reveal Subclinical Cardiomyocyte Dysfunction Associated With the CAV3 N‐Terminal Variant p.Ala46Thr

The CAV3 p.Ala46Thr mutation is previously associated with skeletal muscle damage only, with its myocardial impact and long‐term cardiac risks unclear. This study is aimed at investigating whether it induces subclinical myocardial damage at the cellular level and explore its mechanism using a patient‐specific iPSC‐CMs...

Jun-Yi Wang, Xin Zhu, Ya-Qiong Li et al. · Human Mutation · 0 citations

Open access Sep 2026

Cellular senescence of fibro-adipogenic progenitors by STAT5A/GFPT2/O-GlcNAcylation impairs muscle recovery after glucocorticoid-induced injury.

The clinical use of glucocorticoids often leads to skeletal muscle injury, characterized by muscle atrophy and dysfunction. Fibro-adipogenic progenitors (FAPs) play an important role in maintaining muscle homeostasis, but their roles in the recovery of skeletal muscle after glucocorticoid-induced injury remain largely...

Bing-Fei Li, Wei Xiang, Wan-Ru Qi et al. · Pharmacological Research · 0 citations

Open access Aug 2026

Dual-Target Cardiac Regeneration: Controllable Nfyb/Nr3c1 Cointervention Spurs Cardiomyocyte Cytokinesis After Myocardial Infarction.

BACKGROUND Myocardial infarction can cause a massive loss of functional cardiomyocytes, yet effective strategies to stimulate cardiac regeneration remain lacking. A key barrier to adult cardiomyocyte proliferation appears to be cytokinesis inhibition. This study aimed to determine whether combining proliferation stimul...

Bing-Jun Lu, Wujian Liu, Ziyan Ge et al. · Circulation · 0 citations