Sep 2026
Modular Lysosome-Targeting Platform Based on a Multivalent DNA Framework for Programmable Protein Degradation.
This work develops a tetrahedral DNA nanostructure-based multivalent lysosome-targeting antibody platform (TDN-MLYTAB) and demonstrates how programmable DNA nanostructures can overcome persistent bioconjugation challenges, advancing modular therapeutics toward application.
Xin Wan, Quan-Hao Dou, Jia-Lin Zeng et al.
· ACS Applied Materials and In... · 0 citations