Open access
Oct 2026
A circRNA-microRNA-Pdcd1 axis drives microglial activation and retinal ganglion cell degeneration
These findings not only uncover a novel circRNA-mediated mechanism in neurodegeneration but also identify the circAgtpbp1-miR-3098-3p-Pdcd1-microglia axis as a promising therapeutic target for neuroprotective interventions.
Lan-Fang Sun, Xiao-Yu Ke, J.-J. Yu et al.
· Communications Biology · 0 citations