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Jia-Ning Zhao

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Open access Jul 2026

Antidepressant-like effects of ketamine involve CX3CL1/CX3CR1 signaling-mediated synaptic plasticity in the mPFC.

Ketamine, a non-competitive N-methyl-D-aspartate acid (NMDA) receptor antagonist, produces rapid and sustained antidepressant actions, but the underlying molecular mechanism remains unclear. The CX3CL1/CX3CR1 signaling is closely related to mood disorders, and this study aims to investigate its role in ketamine's antid...

Yong-Yu Yin, Si-Rui Sun, Hui-Ying Zhang et al. · 0 citations

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