Jul 2026
CoAff-DTI: Fine-grained drug-target interaction prediction using pre-trained language models and affinity-guided mechanisms
CoAff-DTI is proposed, an end-to-end deep learning framework designed to enhance multi-scale interaction modeling for DTI prediction and consistently outperforms state-of-the-art methods on multiple benchmark datasets.
Jia Peng, Xiaoyu Liu, Lei Wang et al.
· Journal of Biomedical Inform... · 0 citations