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Jia-Qi Cao

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Open access Sep 2026

Akkermansia muciniphila Ameliorates Midlife Obesity-Induced Cognitive Impairment via the Microbiota-Metabolism-Neuroinflammation Axis

Midlife obesity is an established independent risk factor for age-related cognitive decline, yet direct causal experimental evidence and underlying gut microbial mechanisms remain poorly defined. Using a mouse model of high-fat diet (HFD)-induced obesity restricted to the midlife period (6–12 months of age) in male wil...

Xiao-Mei Bian, Jia-Qi Cao, An-Rui He et al. · 0 citations

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