Author

Jiaqi Sun

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Open access Oct 2026

CD73-targeted CAR-NK cell therapy displays potent antitumor activity and translational potential in relapsed/refractory lung adenocarcinoma

Preclinical evidence is provided that CD73-CAR-NK cells exhibit potent antitumor efficacy for R/R LUAD through their dual functions of eliminating CD73-high tumor cells and resisting adenosine-mediated immunosuppressive signaling, supporting their therapeutic potential.

Qian-Qian Liu, Qi-Fei Dong, Yi-Mei Chen et al. · Biomarker Research · 0 citations

Open access Jul 2026

Generation of FCGR3A-EGFP knock-in reporter human embryonic stem cell line, WAe001-A-3S, using CRISPR/Cas9n-based gene targeting.

This reporter line enables real-time tracking of FCGR3A expression during immune cell differentiation, serving as a useful tool for studying FCGR3A-EGFP knock-in human embryonic stem cell (hESC) line via CRISPR/Casn9n.

Qifei Dong, Shahang Luo, Jiaqi Sun et al. · Stem Cell Research · 0 citations