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Jia-Rui Li

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Open access Sep 2026

Stereoselective Synthesis of β-4′-Hydroxymethyl-Deleted Nucleosides via CPA-Ph3PS Cooperative-Catalyzed Iodocyclization

β-4′-Hydroxymethyl-deleted nucleosides are a class of four-carbon-sugar isonucleosides that possess significant research value in medicinal chemistry and artificial genetic polymer science. Nevertheless, current synthetic methodologies are hampered by several drawbacks, including poor diastereoselectivity, considerable...

Qi Wang, Yu-Qian Liu, Yue-Yue Chen et al. · 0 citations

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