Jia-Shen Hu

Bioorthogonal aggregation-induced emission nanoprobes for targeted photodynamic eradication of Gram-negative pathogens in periodontitis

Periodontitis is a bacteria-driven immune–inflammatory disease associated with progressive periodontal tissue destruction and alveolar bone loss. Conventional treatments rely heavily on broad-spectrum antibiotics, which can promote antimicrobial resistance and disrupt the oral microbiota. Herein, we report a bioorthogo...