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Author

Jia-Wei Li

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Aug 2026

Combining adaptive laboratory evolution and metabolic engineering for efficient erythritol production from crude glycerol by Yarrowia lipolytica.

This study demonstrates the effective integration of adaptive evolution with metabolic remodeling for efficient erythritol biosynthesis in Yarrowia lipolytica mutants through adaptive laboratory evolution under hyperosmotic stress.

Ling-Xuan Zhao, Jia-Wei Li, Ya-Ting Wang et al. · 0 citations
Open access Aug 2026

Genome-integrated engineering of Escherichia coli Nissle 1917 enables sustained gut-local biosynthesis of 5-hydroxytryptophan

A genome-integrated engineered probiotic system enabling gut-local biosynthesis of 5-HTP was developed and results showed that the hTPH2 hydroxylation module, together with the BH4 biosynthesis and regeneration system, supported 5-HTP biosynthesis in EcN.

Jing Wu, Yifan Yang, Taiyu Li et al. · 0 citations

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