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Jia-Wei Shao

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Open access Aug 2026

FOXP1 transcriptionally activates NUSAP1 to induce M2 polarization of tumor-associated macrophages via glycolysis in hepatocellular carcinoma

A novel mechanism by which FOXP1 transcriptionally upregulates NUSAP1 expression results in glycolytic metabolic reprogramming that induces TAM M2 polarization and promotes HCC progression, identifying a potential therapeutic avenue for reversing the immunosuppressive microenvironment in HCC.

Zhi-Wei Wang, Yu-Yi Mao, Jian-Gang Wang et al. · 0 citations

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