Author

Jia-Wei Yan

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Open access Oct 2026

Hemicyanine-Based Wash-Free Near-Infrared Fluorescent Probe for Imaging Amyloid-β Aggregates in Alzheimer’s Disease

By fine-tuning the amphiphilicity of a hemicyanine scaffold to place its log P within the appropriate range, P3 is identified as a wash-free NIRF probe for Aβ aggregates and provides a wash-free, high-affinity NIRF probe for Aβ imaging.

Xue-Qi Zhao, Run-Dong Liang, Yao Li et al. · Molecules · 0 citations