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Jia-Wei Zhao

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Open access Jul 2026

Physical inactivity in preclinical Alzheimer's disease: Risk factor, early symptom, or both?

Abstract Physical inactivity is a key modifiable risk factor for Alzheimer's disease (AD). However, emerging evidence suggests a bidirectional relationship where inactivity also serves as an early manifestation of AD pathology. This perspective synthesizes recent findings from long‐term epidemiological cohorts, brainst...

Jia-Wei Zhao, Xin Li, Meng-Xuan Wu et al. · 0 citations

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