Sep 2026
A closed-loop language-model agent for target-specific multi-objective hit-to-lead optimization
Wen-Tao Cui, Li-Meng Tian, Xiao-Ning Qi et al.
· bioRxiv · 0 citations
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AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Sep 2026
Multi-Omics-Enabled Precision Strategies for Overcoming CAR-T Therapy Limitations in Gastrointestinal Malignancies.
Gastrointestinal malignancies, including gastric cancer, colorectal cancer, hepatocellular carcinoma, and pancreatic ductal adenocarcinoma, remain major causes of cancer-related morbidity and mortality worldwide. Although chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematologic m...
Ke Su, Zun-Yuan Tan, Han Li et al.
· Biofactors · 0 citations
CellRFT: Reinforcement Fine-Tuning for Single-Cell Perturbation Modeling
Comprehensive experiments demonstrate CellRFT's applicability across different pretrained models and effectiveness in improving perturbation prediction, reveal that optimizing one biological criterion can help or hinder others, and show that complementary rewards can improve criteria beyond those directly optimized.
Jie Yan, Li Liu, Han-Ze Guo et al.
· 0 citations