Open access
Sep 2026
lncRNA Gm10451 mediates β-cell functional impairment in type 1 diabetes through the miR-24-3p/G6PD axis
Pancreatic β-cell dysfunction underlies type 1 diabetes mellitus (T1DM) progression. Previous study showed that lncRNA Gm10451 is upregulated by high glucose and contributes to β-cell impairment, but its mechanism remains unclear. Interactions among Gm10451, miR-24-3p, and G6PD were validated by dual-luciferase assay a...
Jiao Wang, Li-Hai Zhang, Xian-He Wang et al.
· Endocrine · 0 citations