Molecular characterization, microbial recognition and immunomodulatory functions of a novel ladderlectin-like lectin (HoLL-like) from Hexagrammos otakii.
Functional assays revealed that rHoLL-like binds and agglutinates multiple Gram-positive and Gram-negative bacteria in a Ca2+-independent manner and binds pathogen-associated molecular patterns (PAMPs), including lipopolysaccharide (LPS), peptidoglycan (PGN), and poly(I:C) in a dose-dependent manner, showing higher aff...