Predicting Knee Osteoarthritis Radiographic Progression: A Multimodal Diffusion Approach.
OBJECTIVES This study aimed to develop KOA-Diff, a multimodal diffusion model predicting future knee radiographs for accurate, visually interpretable forecasting of knee osteoarthritis (KOA) progression. METHODS KOA-Diff utilizes a latent diffusion backbone and a multimodal fusion network to integrate baseline X-rays...