Construction of a robust fluorescent probe for the rapid evaluation of natural products' inhibition of Alzheimer's disease.
Peroxynitrite (ONOO-) is a key oxidative stress biomarker for Alzheimer's disease (AD), and elevated levels of ONOO- in the brain directly reflect the extent of oxidative stress-induced damage in AD. To enable in situ real-time monitoring of ONOO-, this study designed and synthesized a ratiometric near-infrared fluores...