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Jia-Xing Wang

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Review Open access Sep 2026

CLDN18.2 in pancreatic ductal adenocarcinoma: Biomarker assessment, spatial heterogeneity and therapeutic modality selection

Claudin 18.2 (CLDN18.2) is expressed in a subset of pancreatic ductal adenocarcinomas (PDACs) and is under clinical development as a target for monoclonal antibodies, antibody‐drug conjugates, immune‐cell engagers, and chimeric antigen receptor (CAR) T‐cell therapies. The testing and clinical‐development pathways...

Ru-Yu Tan, Zhe-Xin Zhang, Jia-Xing Wang et al. · 0 citations

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