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Author

Jiaxuan Qiu

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Open access Aug 2026

Cryo-EM structures of Cdr1 reveal snapshots of substrate transport and diverse inhibitor recognition

In Candida albicans—a World Health Organization fungal priority pathogen—overexpression of the adenosine triphosphate (ATP)–binding cassette transporter Cdr1 drives multidrug resistance. We present seven cryo–electron microscopy structures capturing substrate entry and expulsion. An inward-facing transmembrane channel...

Zhen Wang, Shu-Ting Yang, Bin-Yu Zhang et al. · 0 citations
Open access Jul 2026

PEG-GE11-modified nanoplatform for co-delivery of cisplatin and plumbagin in targeted therapy of oral squamous cell carcinoma

This innovative nanoplatform combines active targeting, stimuli-responsive drug release, and chemo-chemodynamic therapy (CCDT), presenting a promising approach to overcome drug resistance and improve the treatment of OSCC.

Zhiliang Nie, Q. Jiang, Xiwen Wan et al. · 0 citations

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