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Author

Jia-Yi Chen

2 papers indexed here

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Review Open access Sep 2026

Lung organoids for preclinical evaluation of stem cell therapies: Opportunities, evidence, and translational challenges

Pulmonary diseases impose a substantial global burden and remain major causes of morbidity and mortality. Despite advances in disease-modifying therapies, effective regenerative treatments remain limited for several chronic lung diseases, including idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease...

Lu-Yu Yang, Yuan-Fang Xing, Jia-Yi Chen et al. · 0 citations
Review Sep 2026

Lactate and lactylation in cancer: metabolic regulation, immune modulation, and therapeutic opportunities.

Lactate has emerged from being viewed as a glycolytic byproduct to a central metabolic and signaling hub that coordinates tumor evolution and therapeutic adaptation. This review integrates current evidence on how lactate production, transport, and accumulation reshape cancer biology, with particular emphasis on the lac...

Jia-Yi Chen, An-Qi He, Si-Yi Zhu et al. · 0 citations

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