Mechanochemical Encapsulation of Enzymes in a Highly Hydrophilic HOF: Harnessing Pore Microenvironment for Enhanced Biocatalysis
Enzymes immobilized within hydrogen‐bonded organic frameworks (HOFs) often suffer from reduced catalytic activity due to mass transfer limitations and pore channel blocking by residual organic solvents from conventional solution‐phase synthesis. In addition, the correlation of HOF pore hydrophilicity‐hydrophobicity...