YTHDF3-Dependent m6A Modification of cGAS Drives Nanoparticle-Induced Senescence in Spermatocytes.
BACKGROUND Nanoplastics (NPs), owing to their small size and ability to cross the blood-testis barrier, pose a potential risk to the male reproductive system. However, the molecular mechanisms underlying NP-induced reproductive toxicity, particularly cell senescence, remain poorly understood. OBJECTIVES This study ai...